A chromosome-scale genome assembly and functional studies implicate the viral RNA polymerase in transcription of most Microplitis demolitor bracovirus late genes.

Kelly T Eidson, Corinne M Stouthamer, Tyler J Simmonds, Sheina B Sim, Scott M Geib, Michael R Strand, Gaelen R Burke

Abstract read

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Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Kelly T EidsonDepartment of Entomology, University of Georgia, Athens, Georgia, USA.

Corinne M StouthamerDepartment of Entomology, University of Georgia, Athens, Georgia, USA.

Tyler J SimmondsDepartment of Entomology, University of Georgia, Athens, Georgia, USA.

Sheina B SimTropical Pest Genetics and Molecular Biology Research Unit, USDA-ARS Daniel K Inouye U.S. Pacific Basin Agricultural Research Center, USDA ARS, Hilo, Hawaii, USA.

Scott M GeibTropical Pest Genetics and Molecular Biology Research Unit, USDA-ARS Daniel K Inouye U.S. Pacific Basin Agricultural Research Center, USDA ARS, Hilo, Hawaii, USA.

Michael R StrandDepartment of Entomology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-1844-7460

Gaelen R BurkeDepartment of Entomology, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-3472-0420

Funding

National Science Foundation 2406367U.S. Department of Agriculture 2040-30400-003-000D, 0201-88888-003-000D, 0201-88888-002-000DU.S. Department of Agriculture 7006700U.S. Department of Agriculture 7006792

6 · The paper itself

Abstract

Microgastroid parasitoids lay eggs in other insects and harbor bracoviruses (BVs), which evolved from a nudivirus. BV genomes are endogenized in the wasp germline and consist of nudivirus-like genes plus proviral segments with virulence genes. Nudivirus genes produce virions in the ovary calyx cells, which wasps use to transfer virulence genes to hosts. Here, we report a chromosome-scale genome assembly for

Indexed as

DNA-Directed RNA PolymerasesGenome, ViralPolydnaviridaeViral ProteinsViral TranscriptionWaspsAnimalsGene Expression Regulation, ViralGenes, ViralTranscription, GeneticDNA-Directed RNA PolymerasesViral Proteinsbracovirusendogenous virus elementgenomeparasitoidpolymerasevirus

Identifiers

PMID42466863

DOI10.1128/jvi.00506-26

PMCPMC13483298

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.