Evidence map›Paper›PMID 42466824›Full record

ArticleAmerican journal of hematology2026

A Multicenter, Open-Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST).

Kenneth I Ataga, Pablo Bartolucci, Santosh L Saraf, Vimal K Derebail, Adlette Inati, Jeffrey D Lebensburger, Laurie DeBonnett, Rodolfo D Cancado, Claire C Sharpe

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kenneth I AtagaUTHSC Center for Sickle Cell Disease, Memphis, Tennessee, USA.ORCID https://orcid.org/0000-0002-4501-9982
Pablo BartolucciUniv Paris Est Créteil, Hôpitaux Universitaires Henri Mondor, APHP, Coordinating Referral Center for Sickle Cell Disease and Red Blood Cell Disorders-UMGGR, Créteil, France.
Santosh L SarafComprehensive Sickle Cell Center, University of Illinois Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-8584-4194
Vimal K DerebailUNC Kidney Center, Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-7662-7497
Adlette InatiLAU Gilbert and Rose-Marie Chaghoury School of Medicine, Byblos and Division of Pediatric Hematology Oncology and Comprehensive Sickle Cell Program, NINI Hospital, Tripoli, Lebanon.ORCID https://orcid.org/0000-0002-9187-5974
Jeffrey D LebensburgerUniversity of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0001-5011-1022
Laurie DeBonnettNovartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.
Rodolfo D CancadoHospital Samaritano, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0003-3269-3780
Claire C SharpeDepartment of Renal Medicine, King's College Hospital, London, UK.ORCID https://orcid.org/0000-0003-1704-8492

Funding

Novartis Pharma AG
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42466824
PMCPMC13540331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.