Evidence map›Paper›PMID 42466819›Full record

ArticleInternational journal of urology : official journal of the Japanese Urological Association2026

A Nationwide Descriptive Analysis of Real-World Outcomes After Radical Prostatectomy in Japan Using the National Clinical Database.

Shinichi Sakamoto, Kyoko Yamamoto, Hiroyuki Yamamoto, Shingo Hatakeyama, Ryuichi Mizuno, Takahiro Yasui, Toshiyuki Kamoto, Eiji Kikuchi, Akihiro Ito, Haruki Kume

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Article in International journal of urology : official journal of the Japanese Urological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shinichi SakamotoNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0002-7508-7521
Kyoko YamamotoDepartment of Healthcare Quality Assessment, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0003-1801-1234
Hiroyuki YamamotoNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3337-7595
Shingo HatakeyamaNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0026-4079
Ryuichi MizunoNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0002-1507-1421
Takahiro YasuiNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2197-2477
Toshiyuki KamotoNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0002-7728-289X
Eiji KikuchiNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0002-1624-6676
Akihiro ItoNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7224-1100
Haruki KumeNational Clinical Database Steering Committee of Japanese Urological Association, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9841-0857

Funding

Japanese Urological Associatoin
6 · The paper itself

Abstract

objectivesTo evaluate real-world biochemical recurrence-free survival (BCRFS) after radical prostatectomy (RP) for prostate cancer in Japan using nationwide data from the National Clinical Database (NCD).

methodsThis study included patients who underwent RP between April and December 2018 and were registered in the NCD from 647 participating institutions. BCRFS was estimated using the Kaplan-Meier method. Outcomes were evaluated according to surgical approach and clinicopathological factors without adjustment for baseline characteristics.

resultsA total of 14 992 patients with available 5-year postoperative follow-up data were included in the analysis. Robot-assisted RP accounted for the majority of procedures (73.2%), followed by open RP (16.0%) and laparoscopic RP (10.8%). The overall 5-year BCRFS rate was 81%. BCRFS was comparable across age groups and surgical approaches. In contrast, pathological factors strongly influenced prognosis. Five-year BCRFS decreased with increasing pathological stage (pT2, 86%; pT3, 65%; pT4, 41%) and was lower in patients with nodal metastasis (pN0, 81%; pN1, 59%). The International Society of Urological Pathology (ISUP) Grade Group demonstrated a stepwise association with prognosis, with 5-year BCRFS declining from 92% in grade group 1 to 60% in grade group 5. Five-year BCRFS was lowest in the extended lymph node dissection group (73%), followed by the obturator lymph node dissection group (80%) and the no-dissection group (87%).

conclusionsCurrent nationwide data delineate the real-world oncological outcomes following RP in Japan. Pathological tumor characteristics-rather than patient age or surgical approach-were the predominant determinants of postoperative prognosis. These findings may provide essential benchmarks to guide clinical decision-making.

Indexed as

Neoplasm Recurrence, LocalProstatectomyProstatic NeoplasmsAgedDatabases, FactualDisease-Free SurvivalFollow-Up StudiesHumansJapanKaplan-Meier EstimateLaparoscopyMaleMiddle AgedNeoplasm StagingPrognosisProstateJapannational clinical database (NCD)prostate cancerrobot assisted radical prostatectomy (RARP)

Identifiers

PMID42466819
PMCPMC13377924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.