ArticleJournal of the American Heart Association2026
Characteristics of Bipolar and Unipolar Electrograms at Optimal Ablation Sites for Ventricular Arrhythmias Originating Near the Left Ventricular Summit.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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17 authors.
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Abstract
backgroundVentricular arrhythmias (VAs) arising near the left ventricular (LV) summit are often successfully ablated from adjacent anatomic sites. However, the role of bipolar and unipolar electrograms in guiding optimal ablation remains unclear. This study aimed to investigate whether bipolar and unipolar electrogram characteristics can help identify the most effective ablation sites for VAs near the LV summit.
methodsWe retrospectively analyzed patients with idiopathic VAs originating from the LV summit, excluding those with structural heart disease or reentrant mechanisms. Electrograms were evaluated at the earliest activation sites within the great cardiac vein/anterior interventricular vein, aortic sinus of Valsalva, subvalvular LV regions, and the right ventricular outflow tract. Bipolar local activation time (LAT
resultsA total of 78 patients (mean age, 53.9±16.6 years; 59 men) with 80 VAs and 229 mapping points (60 in the great cardiac vein/anterior interventricular vein, 62 in the aortic sinus of Valsalva, 65 in subvalvular LV regions, and 42 in the right ventricular outflow tract) were analyzed. Ablation was successful at 65 sites. The mean LAT
conclusionsEarly LAT
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