Evidence map›Paper›PMID 42466232›Full record

ArticleCase reports in obstetrics and gynecology2026

Ovary Preservation for Cervical Clear Cell Adenocarcinoma in an 8-Year-Old Girl: A Novel Approach.

Lin Wang, Weiguo Hu, Jinqiu Zhang, Angang Sun, Yu Chen, Huijian Li, Shaojie Zhao, Dengxin Zhang, Yue Wu, Qi Chen and 2 more

Abstract read
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In one paragraph

Article in Case reports in obstetrics and gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lin WangDepartment of Gynaecological Oncology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Weiguo HuDepartment of Gynaecological Oncology, Hospital of Obstetrics and Gynaecology, Fudan University, Shanghai, China, fudan.edu.cn.
Jinqiu ZhangDepartment of Pathology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Angang SunDepartment of Pathology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Yu ChenDepartment of Reproductive Endocrinology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Huijian LiDepartment of Gynaecological Oncology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Shaojie ZhaoDepartment of Gynaecology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Dengxin ZhangDepartment of Anesthesia, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Yue WuDepartment of Gynaecological Oncology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.
Qi ChenDepartment of Obstetrics, Gynaecology and Reproductive Science, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand, auckland.ac.nz.ORCID https://orcid.org/0000-0001-5894-6331
Yanfang GuDepartment of Reproductive Endocrinology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.ORCID https://orcid.org/0009-0005-7014-0388
Min ZhaoDepartment of Gynaecological Oncology, Wuxi Maternity and Child Health Hospital, Jiangnan University, Wuxi, China, jiangnan.edu.cn.ORCID https://orcid.org/0000-0002-1335-4495

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical clear cell adenocarcinoma is a rare malignancy in adolescents and young girls. Since the prescription of diethylstilbestrol (DES) was banned in 1971, only 11 cases have been reported in girls under 10 years in the literature. However, treatment with ovary preservation has not been reported. Here, we report an 8-year-old prepubertal girl without a history of exposure to DES who was diagnosed with cervical clear cell adenocarcinoma. Hysterectomy and unilateral oophorectomy were performed. The remaining ovary was transposed to the left iliac fossa to preserve ovarian function for the future. Additionally, ovarian cortical tissue from the removed ovary was cryopreserved. Chemotherapy, including paclitaxel and carboplatin, was started after surgery for four cycles via an implantable venous access port. Additionally, genetic analysis did not identify any known gene mutations in the tumour tissue.

Identifiers

PMID42466232
PMCPMC13373695

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.