SynthesisFrontiers in dental medicine2026
Fracture resistance of teeth obturated with different root canal sealers: a systematic review.
Synthesis in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Endodontically treated teeth are more prone to fracture due to structural loss during canal preparation and alterations in dentin biomechanics. Root canal sealers and obturation materials contribute not only to sealing ability but also to potential reinforcement of the remaining tooth structure. However, their influence on fracture resistance remains unclear due to variability in study designs and outcomes. Objective: To systematically evaluate and synthesize the available evidence on the fracture resistance of endodontically treated teeth obturated with different root canal sealers and materials. Methods: A comprehensive search was conducted across MEDLINE (via PubMed), Scopus, Web of Science, and the Cochrane Library, supplemented by grey literature from Google Scholar. A total of 549 records were identified, of which 24 studies met the eligibility criteria and were included in the qualitative synthesis. Among these, 22 were Results: Obturation with root canal sealers generally improved fracture resistance compared with instrumented but unobturated controls, indicating a reinforcing effect. Epoxy resin-based and calcium silicate-based sealers demonstrated comparable performance, while zinc oxide eugenol-based sealers showed limited reinforcement. Considerable heterogeneity in tooth selection, loading conditions, and testing protocols limited direct comparisons. Conclusion: Root canal sealers appear to enhance the mechanical strength of endodontically treated teeth; however, no specific sealer demonstrates clear superiority. Standardized experimental models and clinical studies are needed to determine their clinical significance. Systematic Review Registration: Unique Identifier, CRD420251163273.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.