ReviewAdvanced biosystems2018
Origami Biosystems: 3D Assembly Methods for Biomedical Applications.
Review in Advanced biosystems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Dimple-Encoded Reprogrammable Origami.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Soft 3D electromagnetic structures with rapid, complex shape morphing.Science advances · 2025Article
- Design and characterization of electroactive gelatin methacrylate hydrogel incorporated with gold nanoparticles empowered with parahydroxybenzaldehyde and curcumin for advanced tissue engineering applications.Journal of materials science. Materials in medicine · 2024Article
- Aptamer-engineered (nano)materials for theranostic applications.Theranostics · 2023Review
- Advances in Biodegradable Soft Robots.Polymers · 2022Review
- 4D Multiscale Origami Soft Robots: A Review.Polymers · 2022Review
- Soft shape-programmable surfaces by fast electromagnetic actuation of liquid metal networks.Nature communications · 2022Article
- Modeling Self-Rollable Elastomeric Films for Building Bioinspired Hierarchical 3D Structures.International journal of molecular sciences · 2022Article
- Spinning-enabled wireless amphibious origami millirobot.Nature communications · 2022Article
- Research Progress on the Flexibility of an Implantable Neural Microelectrode.Micromachines · 2022Review
- Recent advances in aptamer-based targeted drug delivery systems for cancer therapy.Frontiers in bioengineering and biotechnology · 2022Review
- Smart and Biomimetic 3D and 4D Printed Composite Hydrogels: Opportunities for Different Biomedical Applications.Biomedicines · 2021Review
- A therapeutic convection-enhanced macroencapsulation device for enhancing β cell viability and insulin secretion.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Origami-Inspired Approaches for Biomedical Applications.ACS omega · 2021Review
- 4D Printing: A Review on Recent Progresses.Micromachines · 2020Review
- Morphological Transformation between Flat and Tube Structures by Coordinated Motions of Soft Pneumatic Microactuators.Scientific reports · 2019Article
- Magnetic origami creates high performance micro devices.Nature communications · 2019Article
- Buckling and twisting of advanced materials into morphable 3D mesostructures.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Electroactive Smart Polymers for Biomedical Applications.Materials (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conventional assembly of biosystems has relied on bottom-up techniques, such as directed aggregation, or top-down techniques, such as layer-by-layer integration, using advanced lithographic and additive manufacturing processes. However, these methods often fail to mimic the complex three dimensional (3D) microstructure of naturally occurring biomachinery, cells, and organisms regarding assembly throughput, precision, material heterogeneity, and resolution. Pop-up, buckling, and self-folding methods, reminiscent of paper origami, allow the high-throughput assembly of static or reconfigurable biosystems of relevance to biosensors, biomicrofluidics, cell and tissue engineering, drug delivery, and minimally invasive surgery. The universal principle in these assembly methods is the engineering of intrinsic or extrinsic forces to cause local or global shape changes via bending, curving, or folding resulting in the final 3D structure. The forces can result from stresses that are engineered either during or applied externally after synthesis or fabrication. The methods facilitate the high-throughput assembly of biosystems in simultaneously micro or nanopatterned and layered geometries that can be challenging if not impossible to assemble by alternate methods. The authors classify methods based on length scale and biologically relevant applications; examples of significant advances and future challenges are highlighted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.