Evidence map›Paper›PMID 42465842›Full record

ArticleFrontiers in cellular and infection microbiology2026

Predictors for identifying autoimmune encephalitis in pediatric patients.

Yanmeng Sun, Shangmin Yang, Mengyuan Wang, Huan Xu, Shifu Wang

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Yanmeng SunDepartment of Microbiology Laboratory, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, China.
Shangmin YangDepartment of Microbiology Laboratory, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, China.
Mengyuan WangDepartment of Microbiology Laboratory, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, China.
Huan XuDepartment of Scientific Affairs, Vision Medicals Center for Infectious Diseases, Guangzhou, China.
Shifu WangDepartment of Microbiology Laboratory, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to identify the independent predictors and develop a predictive model for autoimmune encephalitis (AE) in pediatric populations. Methods: This retrospective study comprised 88 pediatric patients with encephalitis (37 AE cases and 51 non- AE cases) at Children's Hospital Affiliated to Shandong University between May 2020 and April 2025. Lasso regression analysis, univariate and multivariate logistic analysis was used to identify autoimmune encephalitis associated risk factors. The nomogram visualized the results. Receiver operating characteristic (ROC) curves, calibration plots, Brier scoring and decision curve analysis (DCA) were used to evaluate the diagnostic model. Results: 16 clinical variables significantly differed between the autoimmune encephalitis and non-autoimmune encephalitis groups. Lasso regression analysis, univariate and multivariate logistic analysis identified four significant independent predictors: age (OR: 1.44; 95% CI: 1.09-1.91; Conclusions: This study established and validated a high-performance predictive model incorporating four clinically accessible parameters for the diagnosis of pediatric autoimmune encephalitis.

Indexed as

EncephalitisHashimoto DiseaseAdolescentChildChild, PreschoolFemaleHumansInfantMaleNomogramsRetrospective StudiesRisk FactorsROC Curveautoimmune encephalitismetagenomic next-generation sequencingpediatricspredictorsROC curve

Identifiers

PMID42465842
PMCPMC13372578

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