ArticleACG case reports journal2026
Malignant Hepatic Infiltration Versus Drug-Induced Liver Injury in B-Cell Acute Lymphoblastic Leukemia.
Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
B-cell acute lymphoblastic leukemia (B-ALL) is the most common subtype of lymphoid malignancy. Elevated liver enzymes in B-ALL may reflect both hepatic infiltration and chemotherapy-related drug-induced liver injury. This creates a diagnostic challenge that can be delineated with a liver biopsy, preventing delays in management and care. We present 2 patients with B-ALL who developed elevated liver enzymes during chemotherapy and underwent liver biopsy demonstrating hepatic infiltration. These biopsy-proven cases highlight the critical role of liver biopsy in distinguishing hepatic infiltration from drug-induced liver injury, guiding management decisions and allowing for continued chemotherapy without unnecessary delay.
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