ArticleACG case reports journal2026
Colonic Ischemia Without Mesenteric Occlusion: A Case Implicating Interferon-β.
Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type I interferons are commonly used immunomodulatory agents. Interferon-α (interferon-α) has been associated with ischemic colitis, but cases linking interferon-β (IFN-β) to ischemic colitis are rare. We present a 66-year-old woman with multiple sclerosis treated with IFN-β who developed acute abdominal pain and diarrhea. Imaging demonstrated right-sided colonic inflammation with pneumatosis. Colonoscopy with tissue biopsy confirmed ischemic colitis, despite patent mesenteric vasculature on angiographic imaging. Her symptoms resolved after discontinuation of IFN-β. This case highlights IFN-β as a potential cause of nonocclusive ischemic colitis and underscores the importance of recognizing ischemic complications in patients treated with IFN-β.
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