Evidence map›Paper›PMID 42465789›Full record

ReviewIndian journal of urology : IJU : journal of the Urological Society of India

Effectiveness and safety of polyacrylamide hydrogel injection for female stress urinary incontinence: A systematic review and single-arm meta-analysis.

Hendri Tanjaya, Amaditta Jericka, Mutiara Riani, Budi Darmawan, Edihan Mardjuki, Jennifer Uriah, Erik Noverdian Suryadi

Abstract readReview
In one paragraph

Review in Indian journal of urology : IJU : journal of the Urological Society of India. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hendri TanjayaSchool of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Amaditta JerickaSchool of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Mutiara RianiDepartment of Obstetrics and Gynecology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Budi DarmawanDepartment of Obstetrics and Gynecology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Edihan MardjukiDepartment of Obstetrics and Gynecology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Jennifer UriahDepartment of Obstetrics and Gynecology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
Erik Noverdian SuryadiDepartment of Obstetrics and Gynecology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Polyacrylamide hydrogel (PAHG) injection is a minimally invasive treatment option for female stress incontinence, but reported effectiveness and durability vary across studies. This study aims to evaluate the effectiveness, safety, and retreatment rates of PAHG injection for female SUI through a systematic review and meta-analysis. Methods: A systematic review and meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines and registered in PROSPERO (CRD420261328968). Literature was retrieved from electronic databases, such as PubMed, ProQuest, EuroPMC, and EBSCO, from database inception through February 2026. Cohort studies assessing PAHG injection for SUI were systematically reviewed. Random-effects models were used, heterogeneity was assessed with Results: Thirteen studies, including 1797 patients, were analyzed. The pooled responder rate was 72% (95% confidence interval [CI] 64%-78%; Conclusion: PAHG injection is a minimally invasive treatment associated with clinically meaningful symptom improvement and a favorable safety profile in women with SUI. However, given the single-arm design of the included studies and substantial heterogeneity, these findings should be interpreted with caution.

Identifiers

PMID42465789
PMCPMC13374942

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.