ArticleCureus2026
Primary Gingival Mucosal Melanoma: A Case Report and Comparison With Cutaneous Melanoma.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mucosal melanoma (MM) is a rare and highly aggressive malignancy arising from melanocytes located within mucosal surfaces. Unlike cutaneous melanoma (CM), MM develops in non-sun-exposed mucosa, frequently harbors KIT or SF3B1 mutations, demonstrates a lower tumor mutational burden, and exhibits reduced responsiveness to immunotherapy. These biological differences distinguish MM from CM and contribute to important differences in staging, prognosis, and management. We describe the case of a 71-year-old male who presented with a newly identified pigmented lesion involving the right inferior gingival mucosa. His medical history included type 2 diabetes mellitus, dyslipidemia, and essential hypertension. Biopsy confirmed malignant MM. Positron emission tomography/computed tomography (PET/CT) demonstrated a 1.3 × 1.2 cm fluorodeoxyglucose-avid lesion (SUV max 9.6) without evidence of mandibular invasion, cervical nodal disease, or distant metastasis. The patient underwent radical excision of the lesion with right selective neck dissection (levels I-III). Histopathologic examination confirmed MM (pT3N1) with positive deep margins and metastatic involvement of two regional lymph nodes. This case highlights the diagnostic and therapeutic challenges of oral MM and emphasizes the importance of recognizing the biological and clinical differences between MM and CM. Routine, thorough intraoral soft-tissue examination and early biopsy of suspicious pigmented oral lesions are essential to facilitate timely diagnosis and management of this aggressive malignancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.