Evidence map›Paper›PMID 42465677›Full record

ReviewJournal of experimental orthopaedics2026

Femoral extra-physeal ACL reconstruction in skeletally immature patients shows a low rate of clinically relevant growth disturbances: A systematic review.

Lorenzo Bini, Tosca Cerasoli, Claudio Rossi, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini, Alberto Grassi

Abstract readReview
In one paragraph

Review in Journal of experimental orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorenzo BiniDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.ORCID https://orcid.org/0009-0005-7035-7050
Tosca CerasoliDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.ORCID https://orcid.org/0000-0003-1111-5869
Claudio RossiDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.
Giulio Maria Marcheggiani MuccioliDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.ORCID https://orcid.org/0000-0002-1087-2932
Stefano ZaffagniniDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.ORCID https://orcid.org/0000-0002-2941-1407
Alberto GrassiDepartment of Biomedical and Neuromotor Sciences (DIBINEM) University of Bologna Bologna Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Physeal-sparing techniques aim to reduce growth disturbances after anterior cruciate ligament reconstruction (ACLR) in skeletally immature patients, but evidence on femoral extra-physeal approaches remains limited. The aim of this study was to systematically review the literature on femoral extra-physeal ACLR in patients with open physes and to evaluate the reported incidence and severity of growth disturbances, including potential influencing factors, such as surgical technique and lateral extra-articular tenodesis. Methods: A systematic search was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies including skeletally immature patients undergoing ACL reconstruction with femoral extra-physeal techniques were included. Growth disturbances were defined as limb length discrepancy or angular deformity. Graft failure was defined as graft rupture, revision surgery or recurrent instability. Results: A total of 579 patients were included with a mean age of 12 years. The over-the-top technique was used in 176 patients, the Kocher-Micheli technique in 327 and the Clocheville technique in 76. Growth disturbances were reported in 26 patients (4.5%); overgrowth was the most frequent pattern. Most of the growth disturbances were minor (3.8%). No patient required surgical correction. Graft failure occurred in 30 patients (5.2%). Conclusion: Paediatric ACL reconstruction using femoral extra-physeal techniques was associated with a low rate of clinically relevant growth disturbances. Most deformities were mild, and no corrective procedure was required. The graft failure rate was also low. These findings should be interpreted with caution given the heterogeneity of the included studies. Level of Evidence: Level IV.

Indexed as

anterior cruciate ligamentgrowth disturbancespaediatricphyseal‐sparingskeletally immature

Identifiers

PMID42465677
PMCPMC13375080

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