Evidence map›Paper›PMID 42465630›Full record

ArticleFrontiers in public health2026

Environmental, biological and cognitive monitoring of children in European primary schools: LEARN crossover study protocol.

Daphne P Berden, Wai Kei Chu, Ernesto Alfaro-Moreno, Vibeke Heitmann Gutzke, Charikleia Karakosta, Katie Kedwell-Simmering, Varun Kumar, Andreas Massling, Karin Rosenkilde Laursen, Andreas Scope and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06197477 (Development of Novel Assessments for Indoor Air Quality Monitoring and Impact on Children's Health - Cohorts in Schools & Biomarkers of Exposure), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06197477 naunknown statusnot on this map

Development of Novel Assessments for Indoor Air Quality Monitoring and Impact on Children's Health - Cohorts in Schools & Biomarkers of Exposure

TypeinterventionalSponsorHasselt UniversityRan2023 to 2025Enrolled900ConditionsCognitionArmsOurAir SQ 1750 - Mobile Air Purification System for indoor, Sham intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daphne P Berden *Centre for Environmental Sciences, Environmental and Molecular Epidemiology, Hasselt University, Diepenbeek, Belgium.
Wai Kei Chu *Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Ernesto Alfaro-MorenoInternational Iberian Nanotechnology Laboratory, Braga, Portugal.
Vibeke Heitmann GutzkeDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Charikleia KarakostaEnvirometrics Technical Consultants SA, Chalandri, Greece.
Katie Kedwell-SimmeringAdvanced Technology, MANN+HUMMEL GmbH, Ludwigsburg, Germany.
Varun KumarDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Andreas MasslingDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Karin Rosenkilde LaursenDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Andreas ScopeAdvanced Technology, MANN+HUMMEL GmbH, Ludwigsburg, Germany.
Carina Veeckmanimec-SMIT-Vrije Universiteit Brussel, Brussels, Belgium.
Rossella AlfanoCentre for Environmental Sciences, Environmental and Molecular Epidemiology, Hasselt University, Diepenbeek, Belgium.
Jeroen A J VanoirbeekCentre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Tim S NawrotCentre for Environmental Sciences, Environmental and Molecular Epidemiology, Hasselt University, Diepenbeek, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor indoor air quality (IAQ) in schools is of particular concern as it can negatively impact children's cognitive development, health, and well-being. Measuring IAQ-related parameters, assessing children's internal and external exposures, and developing solutions for reducing exposure are therefore critical to protecting children's health. The use of air purifiers can be a good mitigation strategy to improve IAQ in classrooms, but their association with health effects and cognitive outcomes in children remains unclear. The LEARN crossover study protocol aims to address this gap by evaluating the impact of a novel air purification intervention on IAQ, biomarkers of exposure, clinical health parameters, and cognitive performance in primary school children ( Clinical trial registration: https://clinicaltrials.gov/study/NCT06197477, Identifier NCT06197477.

Indexed as

Air Pollution, IndoorBiological MonitoringCognitionEnvironmental ExposureEnvironmental MonitoringSchoolsBiomarkersChildCross-Over StudiesEuropeFemaleHumansMaleSingle-Blind MethodBiomarkersair remediationbiomonitoringcognitive performancecrossover study designindoor air pollutantsschool-aged childrenstudy protocol

Identifiers

PMID42465630
PMCPMC13373876

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.