ArticleFrontiers in cardiovascular medicine2026
Association of intraluminal thrombus in thoracoabdominal aortic aneurysms with a blood stasis model.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The aim of this study was to perform patient-specific hemodynamic simulations of thoracoabdominal aortic aneurysm (TAAA) models and evaluate the potential for intraluminal thrombus (ILT) formation. Methods: Computed Tomography Angiography data from 12 TAAA patients were reconstructed into patient-specific models, which were grouped according to the presence or absence of ILT accumulation. Old blood volume fraction (OBVF) and convergence time were proposed to reveal the association between thrombotic potential and blood stasis in TAAA. Results: The aneurysm exhibited high blood stasis compared with other parts. In the ILT group, normalized OBVF and convergence time (a passive-tracer washout time, not a physiological thrombosis timescale) were 76.66% ± 12.38% and 42.58 ± 13.29 s, respectively, whereas in the non-ILT group, they were 21.42% ± 3.39% and 10.93 ± 5.96 s. The OBVF and convergence time were significantly greater in the ILT group than in the non-ILT group ( Conclusion: The blood stasis model provides a new and intuitive approach for clinicians to diagnose and treat ILT in TAAA, offering clearer insights than parameters related to WSS. This model can provide useful guidance for operative planning and postoperative evaluation.
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