Evidence map›Paper›PMID 42465527›Full record

ArticleCase reports in infectious diseases2026

Pulmonary Nocardiosis Diagnosed by Plasma Metagenomic Next-Generation Sequencing in a Patient With Recurrent Febrile Neutropenia.

Maria Vega Brizneda, Jessica Lum, Hannah Wang, Zachary A Yetmar

Abstract read
In one paragraph

Article in Case reports in infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Vega BriznedaDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0001-6729-0880
Jessica LumDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0001-6040-4304
Hannah WangDepartment of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0002-3712-9188
Zachary A YetmarDepartment of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA, clevelandclinic.org.ORCID https://orcid.org/0000-0003-2098-2868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nocardiosis disproportionately affects immunocompromised hosts. Early identification of Case Presentation: We report a case of pulmonary nocardiosis in an 87-year-old man with myelodysplastic syndrome and prolonged neutropenia diagnosed by plasma mNGS. He had been hospitalized multiple times with recurrent febrile neutropenia and respiratory symptoms. Standard noninvasive microbiologic workup was unrevealing, but lower respiratory specimens could not be readily obtained. Due to elevated risk of complications from invasive testing, plasma mNGS was used as a complementary tool and identified Conclusion: mNGS is an emerging diagnostic tool that may identify

Indexed as

KariusmNGSneutropeniaNocardia farcinicanocardiosis

Identifiers

PMID42465527
PMCPMC13373437

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.