Evidence map›Paper›PMID 42465520›Full record

ArticlebioRxiv : the preprint server for biology2026

A dual-function regulatory element couples ParB expression and DNA substrate specificity.

Rodrigo A Arana-Garrido, Daniel Lee Joo, Huda Al-Zuhairi, John D Norcross, Ariana N Nielsen, HyeongJun Kim, Paola E Mera

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rodrigo A Arana-GarridoDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL.
Daniel Lee JooDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL.
Huda Al-ZuhairiDepartment of Physics and Astronomy, University of Texas Rio Grande Valley, Edinburg, TX.
John D NorcrossDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL.
Ariana N NielsenDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL.
HyeongJun KimDepartment of Physics and Astronomy, University of Texas Rio Grande Valley, Edinburg, TX.ORCID 0000-0002-3769-2632
Paola E MeraDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL.ORCID 0000-0003-3761-3786

Funding

Molecular basis of bacterial chromosome segregation and organizationR35GM143093 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI KIM, HYEONGJUN · 2021 to 2025
$2.0M
Deciphering the molecular circuitry that controls cell cycle progression in bacteriaR01GM133833 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MERA, PAOLA E · 2019 to 2023
$1.7M
Decoding the rules that govern the coordination of the bacterial cell cycleR35GM158016 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Paola E Mera · 2025 to 2026
$997k
NIGMS NIH HHS R01 GM133833NIGMS NIH HHS R35 GM143093NIGMS NIH HHS R35 GM158016
6 · The paper itself

Abstract

Chromosome segregation is essential for cell survival. Most bacteria encode the chromosome partitioning ParABS system. Although even small changes in ParA or ParB levels disrupt genome maintenance, the mechanisms that control their abundance have remained unresolved. Using

Indexed as

Caulobacter crescentusChromosome segregationParABSParBpost-transcriptional regulation

Identifiers

PMID42465520
PMCPMC13371061

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.