Evidence map›Paper›PMID 42465404›Full record

ArticlebioRxiv : the preprint server for biology2026

Multiscale harmonization, semantic integration, and immersive exploration of single-cell data in support of novel biological insights.

Andreas Bueckle, Chenchen Zhu, Alex Y H Wong, Archibald Enninful, Yang Miao, Negin Farzad, Maria Pedersen, Courteney Mattison, Nicholas Sloan, Jason Mares and 17 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Andreas BueckleDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-8977-498X
Chenchen ZhuDepartment of Genetics, Stanford University, Stanford, CA, USA.ORCID 0000-0003-2165-9456
Alex Y H WongLaboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9315-4145
Archibald EnninfulSchool of Engineering & Applied Science, Yale University, New Haven, CT, USA.ORCID 0000-0002-6350-6530
Yang MiaoDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0009-0002-3464-8203
Negin FarzadSchool of Engineering & Applied Science, Yale University, New Haven, CT, USA.ORCID 0009-0002-5391-9363
Maria PedersenCenter for Genomics of Neurodegenerative Disease, New York Genome Center, New York, NY, USA.ORCID 0000-0003-0034-5837
Courteney MattisonCenter for Genomics of Neurodegenerative Disease, New York Genome Center, New York, NY, USA.ORCID 0009-0004-6241-7837
Nicholas SloanCenter for Genomics of Neurodegenerative Disease, New York Genome Center, New York, NY, USA.ORCID 0000-0001-5261-7326
Jason MaresDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0009-0009-4343-0530
Cheng XingThe Donnelly Centre, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-7959-6403
Bruce W HerrDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-6703-7647
Juhi KhareDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0009-0000-0603-2255
Yash KumarDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0009-0002-3750-9129
Keyur ParekhDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0009-0004-7450-8840
Siddhi ChavanDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.
Paean LubyDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0009-0007-6578-5784
Ushma PatelDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-7467-1873
Yashvardhan JainDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-6300-5568
John HickeyDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0001-9961-7673
Gary D BaderThe Donnelly Centre, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-0185-8861
Hemali PhatnaniCenter for Genomics of Neurodegenerative Disease, New York Genome Center, New York, NY, USA.ORCID 0000-0002-6571-3891
Vilas MenonDepartment of Neurology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-4096-8601
Rong FanSchool of Engineering & Applied Science, Yale University, New Haven, CT, USA.ORCID 0000-0001-7250-7546
Peter K SorgerLaboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3364-1838
Michael SnyderDepartment of Genetics, Stanford University, Stanford, CA, USA.ORCID 0000-0003-0784-7987
Katy BörnerDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.ORCID 0000-0002-3321-6137

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-cell atlassing efforts like the Human BioMolecular Atlas Program (HuBMAP) and Cellular Senescence Network (SenNet) produce multiscale datasets across the healthy, adult, human body but are typically explored on 2D screens with limited 3D affordances, even though understanding cell location within tissue, organ, and body requires spatial reasoning across many orders of magnitude. The Human Reference Atlas (HRA) provides standard terminologies and a Common Coordinate Framework (CCF) for harmonizing this data spatially and semantically. Building on the

Identifiers

PMID42465404
PMCPMC13371083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.