Evidence map›Paper›PMID 42465308›Full record

ArticlebioRxiv : the preprint server for biology2026

Perturbations shift the composition of bacterial DNA carried by virus-like particles in the murine gut microbiome.

Jessie L Maier, Benjamin Callahan, Breck A Duerkop, Manuel Kleiner

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessie L MaierDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC.ORCID 0009-0001-8575-5386
Benjamin CallahanPopulation Health and Pathobiology Department, North Carolina State University, Raleigh, NC.ORCID 0000-0002-8752-117X
Breck A DuerkopDepartment of Immunology and Microbiology, University of Colorado - Anschutz Medical Campus, School of Medicine, Aurora, CO.ORCID 0000-0003-4030-9822
Manuel KleinerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC.ORCID 0000-0001-6904-0287

Funding

DNA transduction in intestinal microbiomes and the spread of pathogenicity traitsR01AI171046 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Breck A Duerkop, Manuel Kleiner · 2024 to 2026
$2.2M
Metaproteomics to investigate intestinal microbiota-host and -diet interactionsR35GM138362 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KLEINER, MANUEL · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI171046NIGMS NIH HHS R35 GM138362
6 · The paper itself

Abstract

Horizontal gene transfer (HGT) is a driving force in microbial evolution that allows community members to rapidly evolve to cope with environmental stressors and competition. Despite the importance of HGT for the generation of genetic diversity, little is known about the specific mechanisms or dynamics of transfer in complex communities. Transductomics is a sequencing based technique which identifies potential HGT by bacteriophages (transduction) through sequencing of the transductome - the DNA carried by bacteriophages and other viruslike particles in a sample. We analyzed the murine gut transductome before and after perturbations with antibiotics and

Identifiers

PMID42465308
PMCPMC13371034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.