Evidence map›Paper›PMID 42465306›Full record

ArticlebioRxiv : the preprint server for biology2026

A Comparative Study of Plasma Biomarkers of Neurodegeneration in Rhesus Monkeys (

Michele M Mulholland, Elizabeth R Magden, Henrieta Scholtzova, William D Hopkins

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michele M MulhollandDepartment of Comparative Medicine, The University of Texas MD Anderson Cancer Center.
Elizabeth R MagdenDepartment of Comparative Medicine, The University of Texas MD Anderson Cancer Center.ORCID 0000-0002-1312-2694
Henrieta ScholtzovaDepartment of Neurology, NYU Grossman School of Medicine.ORCID 0000-0003-0766-9463
William D HopkinsDepartment of Comparative Medicine, The University of Texas MD Anderson Cancer Center.ORCID 0000-0003-3480-1853

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative SupplementP40OD024628 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Joe H. Simmons · 2017 to 2026
$15.7M
Innate Immunity Stimulation Effects on Biomarkers, Cognition, and the Vascular Amyloid Proteome in a Squirrel Monkey Model of Sporadic CAAR01NS128190 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Henrieta Scholtzova · 2022 to 2026
$4.1M
Alzheimer's Disease Pathology in a Primate ModelR01AG067419 · NIA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOPKINS, WILLIAM D · 2021 to 2025
$3.8M
Lifespan and Cardiovascular Health Effects on The Brain in Humans and Great ApeR01AG087945 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Melissa K. Edler, PATRICK R HOF · 2024 to 2026
$2.9M
Relationships between immunosenescence, brain aging biomarkers, and cognition across nonhuman primate species of differing lifespansR01AG087914 · NIA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michele M Mulholland · 2024 to 2026
$2.4M
Baboon model of chemotherapy-related cognitive impairment and accelerated agingK01AG078411 · NIA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Michele M Mulholland · 2022 to 2026
$941k
NCI NIH HHS P30 CA016672NIA NIH HHS K01 AG078411NIA NIH HHS R01 AG067419NIA NIH HHS R01 AG087914NIA NIH HHS R01 AG087945NIH HHS P40 OD024628NINDS NIH HHS R01 NS128190
6 · The paper itself

Abstract

Many nonhuman primate species recapitulate the neuropathological features of sporadic Alzheimer's disease (AD) to varying degrees. As with humans, the assessment of AD-related pathology in nonhuman primates has historically relied on the use of postmortem brain tissues.

Indexed as

agingbiomarkersbrain atrophygray matterneurodegenerationnonhuman primates

Identifiers

PMID42465306
PMCPMC13371045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.