Evidence map›Paper›PMID 42465246›Full record

ArticlebioRxiv : the preprint server for biology2026

PLANCK: super-multiplex optical imaging without labeling.

Xinwen Liu, Xuemeng Li, Lele Xu, Mian Wei, Areej Niaz, Ye He, Wei Min

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinwen LiuDepartment of Chemistry, Columbia University, New York, NY, 10027.
Xuemeng LiDepartment of Chemistry, Columbia University, New York, NY, 10027.
Lele XuAdvanced Science Research Center, City University of New York, New York, NY 10031.
Mian WeiDepartment of Chemistry, Columbia University, New York, NY, 10027.
Areej NiazAdvanced Science Research Center, City University of New York, New York, NY 10031.
Ye HeAdvanced Science Research Center, City University of New York, New York, NY 10031.
Wei MinDepartment of Chemistry, Columbia University, New York, NY, 10027.

Funding

Super-multiplex optical imaging: development of novel spectroscopy and probes to illuminate complex biomedicineR35GM149256 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Wei Min · 2023 to 2026
$2.8M
TimsTOF-fleX MALDI-2 mass-spectrometerS10OD036268 · OD · ADVANCED SCIENCE RESEARCH CENTER · PI ABZALIMOV, RINAT · 2024 to 2024
$1.5M
NIGMS NIH HHS R35 GM149256NIH HHS S10 OD036268
6 · The paper itself

Abstract

Molecular information is vital for imaging technology. Optical imaging acquires molecular specificity almost exclusively via labeling strategy, which is fundamentally constrained by limited multiplexing capacity, high running costs, and experimental complexity. Conversely, label-free optical imaging offers substantial technical simplicity but is believed to have little true molecular specificity. Contrary to common belief, here we introduce

Identifiers

PMID42465246
PMCPMC13370502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.