Evidence map›Paper›PMID 42465181›Full record

ArticleCureus2026

Multimodal Interdisciplinary Management of Level III Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus: The Role of Preoperative Embolization, Intracaval Balloon Control, and Radical Nephrectomy With Inferior Vena Cava Thrombectomy.

Faris Abushamma, Ibraheem Alami, Mohammed Tawfiq Abu Aisheh, Khaled Demyati, Abdelkarim Barqawi, Maha Akkawi, Mohammad Khader, Razan Odeh, Daher Alsadi, Moutaz W Sweileh and 1 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Faris AbushammaDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, PSE.
Ibraheem AlamiDepartment of Urology, An-Najah National University Hospital, Nablus, PSE.
Mohammed Tawfiq Abu AishehDepartment of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, PSE.
Khaled DemyatiDepartment of General Surgery, An-Najah National University Hospital, Nablus, PSE.
Abdelkarim BarqawiDepartment of General Surgery, An-Najah National University Hospital, Nablus, PSE.
Maha AkkawiDepartment of Pathology, An-Najah National University Hospital, Nablus, PSE.
Mohammad KhaderDepartment of Radiology, An-Najah National University Hospital, Nablus, PSE.
Razan OdehDepartment of Hemato-oncology, An-Najah National University Hospital, Nablus, PSE.
Daher AlsadiDepartment of Urology, An-Najah National University Hospital, Nablus, PSE.
Moutaz W SweilehDepartment of Pathology, An-Najah National University Hospital, Nablus, PSE.
Ahmed GhanemDepartment of Radiology, An-Najah National University Hospital, Nablus, PSE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma with tumor thrombus extending into the inferior vena cava (IVC) above the hepatic veins (Mayo level III) is among the most technically demanding scenarios in urooncological surgery. We describe the case of a previously healthy 59-year-old gentleman who presented with a large right renal mass and a 9 cm tumor thrombus extending from the right renal vein into the intrahepatic IVC. After multidisciplinary discussion, the patient underwent a combined urovascular procedure preceded by a same-day interventional radiology (IR) intervention comprising selective right renal artery embolization, embolization of the highly vascular caval tumor thrombus, and the placement of an accommodating intracaval balloon for suprahepatic vascular control. A rooftop incision was used for radical nephrectomy with IVC thrombectomy under triple-level caval control and contralateral renal vein control; intraoperative cavography by the IR team confirmed complete extraction of the thrombus and a patent IVC. Estimated blood loss was minimal, and no transfusion was required. The combination of preoperative selective embolization, intracaval balloon assistance, and intraoperative cavography may improve hemostatic control, reduce the risk of intraoperative tumor embolization, and provide a reproducible adjunct to conventional surgical thrombectomy for level III IVC tumor thrombi. Further prospective studies and larger case series are mandated to define the incremental benefit of each component.

Indexed as

endovascular balloon controlinferior vena cava tumor thrombusintraoperative cavographyivc thrombectomylevel iiimultidisciplinarypreoperative renal artery embolizationrenal cell carcinoma

Identifiers

PMID42465181
PMCPMC13373008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.