Evidence map›Paper›PMID 42465072›Full record

ArticleFrontiers in medicine2026

Characteristics in the uterine cavity microbiota of infertile women with hydrosalpinx or endometrial polyps revealed by shotgun metagenomics.

ShuZhen Li, Huifeng Zeng, Xiulin Wan, Zhiruo Chen, Xia Nong, Lisi Peng, Qingyang Li, Yuxia Wang

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

ShuZhen LiReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Huifeng ZengReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Xiulin WanGenome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, Guangdong, China.
Zhiruo ChenReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Xia NongReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Lisi PengReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Qingyang LiMinistry of Education Key Laboratory of Molecular and Cellular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei, China.
Yuxia WangReproductive Medicine Center, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is a global public health issue, and a favorable endometrial environment is essential for successful assisted reproductive treatment. Endometrial polyps (EM) and hydrosalpinx (HD) are common gynecological disorders impairing the intrauterine milieu, but their impacts on uterine cavity microbiota remain unclear. This study enrolled 75 participants [32 fertile controls (C), 32 EM patients, 11 HD patients] to characterize their uterine cavity profiles using shotgun metagenomic sequencing. The C group showed significantly higher microbial alpha diversity than the two patient groups, with no significant difference between EM and HD groups. At the species level, EM group exhibited marked dysbiosis, characterized by elevated pathogenic bacteria, particularly

Indexed as

endometrial microbiotaendometrial polypshydrosalpinxinfertilitymetagenomic sequencing

Identifiers

PMID42465072
PMCPMC13372777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.