Evidence map›Paper›PMID 42465053›Full record

ArticleJournal of clinical and translational science2026

Development of a pediatric urgent care research infrastructure to facilitate human immunology studies.

John J Santos, Alexandra C Keefe, Richard Torres, Gerson Zaragoza, Caitlin Ginn, Nia Barr-Jeffrey, Holly Barrett, Phoenicia Quach, Katherine Grubb, Whitney E Harrington and 1 more

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John J SantosDivision of Urgent Care, Seattle Children's Hospital, Seattle, WA, USA.
Alexandra C KeefeCenter for Clinical and Translational Research, Seattle Children's Research Institute, Seattle, WA, USA.
Richard TorresResearch Coordinator Core, Seattle Children's Research Institute, Seattle, WA, USA.
Gerson ZaragozaResearch Coordinator Core, Seattle Children's Research Institute, Seattle, WA, USA.
Caitlin GinnCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Nia Barr-JeffreyCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Holly BarrettCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Phoenicia QuachCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, USA.
Katherine GrubbResearch Coordinator Core, Seattle Children's Research Institute, Seattle, WA, USA.
Whitney E HarringtonPediatrics, University of Washington School of Medicine, Seattle, WA, USA.
Blair ArmisteadPediatrics, University of Washington School of Medicine, Seattle, WA, USA.ORCID https://orcid.org/0000-0001-9902-3955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pediatric urgent care setting offers a unique opportunity to enroll pediatric patients and their families to facilitate the study of human immunology. However, it is an underutilized environment for recruiting participants into research studies, most likely driven by a fundamental "conflict of urgency" - the tension between the time-limited nature of acute ambulatory care and the time-intensive requirements of human subjects research. To address this challenge, we implemented a study of infant and maternal immune responses to respiratory tract infection (the MATMilk study) across four Seattle Children's Hospital Urgent Care (SCHUC) clinics using a novel, two-phase study design, which uncoupled initial clinical contact from enrollment and specimen collection. This approach allowed complete remote participation and minimized disruption to clinical workflows. To date, we have enrolled

Indexed as

clinical-research partnershipcohort enrollmenthuman immunology researchPediatric urgent carestudy implementation

Identifiers

PMID42465053
PMCPMC13373604

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.