Evidence map›Paper›PMID 42464779›Full record

Observational studyPediatric pulmonology2026

Current Practices and Variations Among Pediatric Severe Asthma Programs in the United States-The North American Severe Pediatric Asthma Consortium.

Kristina Gaietto, Nadia Krupp, Avani V Shah, Erhan Ararat, Samantha H Averill, Sachin Baxi, Matejka Cernelc-Kohan, Jeffrey M Chambliss, Heather De Keyser, Monica Federico and 22 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pediatric pulmonology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Kristina GaiettoDepartment of Pediatrics, School of Medicine, Division of Pulmonology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-4618-2984
Nadia KruppDivision of Pulmonology Allergy/Immunology and Sleep Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0002-0696-085X
Avani V ShahDivision Pulmonary Ann and Robert H. Lurie Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Erhan AraratDepartment of Pediatrics, Division of Pulmonology, University of Arkansas Medical Sciences, Little Rock, Arkansas, USA.
Samantha H AverillDivision of Pulmonology Allergy/Immunology and Sleep Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Sachin BaxiDepartment of Pediatrics, Harvard Medical School, Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Matejka Cernelc-KohanDivision of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, California, USA.
Jeffrey M ChamblissDepartment of Pediatrics, Division of Pulmonology and Sleep Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Heather De KeyserDepartment of Pediatrics, University of Colorado School of Medicine, Allergy and Immunology Section, Children's Hospital Colorado, Aurora, Colorado, USA.
Monica FedericoDepartment of Pediatrics, Pediatric Pulmonary Medicine, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.
Bob GengDivision of Allergy, Immunology & Rheumatology, University of California San Diego and Rady Children's Hospital, San Diego, California, USA.
Akilah A JeffersonDepartment of Pediatrics, Division of Pulmonology, University of Arkansas Medical Sciences, Little Rock, Arkansas, USA.
Parisa KavianyDivision of Pulmonary and Sleep Medicine, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Lila C KertzWashington University School of Medicine, Division of Pediatric Allergy and Pulmonary Medicine, St Louis, Missouri, USA.
Kirsten KloepferDivision of Pulmonology Allergy/Immunology and Sleep Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0003-1504-8114
Allyson LarkinDepartment of Pediatrics, School of Medicine, Division of Pulmonology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sydney LeibelDivision of Allergy, Immunology & Rheumatology, University of California San Diego and Rady Children's Hospital, San Diego, California, USA.
Tanya Martinez-FernandezDepartment of Pediatrics, Division of Pulmonology and Sleep Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Samira NaimeDivision of Allergy, Immunology, Pulmonary, and Sleep Medicine of Children's Mercy, University of Missouri, Kansas City, Missouri, USA.
Robert D PesekDepartment of Pediatrics, Division of Pulmonology, University of Arkansas Medical Sciences, Little Rock, Arkansas, USA.ORCID https://orcid.org/0000-0002-3136-0039
Dinesh K PillaiDivision of Pulmonary and Sleep Medicine, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Deepa RastogiDivision of Respiratory and Sleep Medicine, Children's Hospital at Montefiore, Albert Einstein College of Medicine, New York, New York, USA.
Katherine Rivera-SpoljaricWashington University School of Medicine, Division of Pediatric Allergy and Pulmonary Medicine, St Louis, Missouri, USA.
Kristie R RossDivision of Pediatric Pulmonary, UH Rainbow Babies and Children's/Case Western Reserve University, Cleveland, Ohio, USA.
Franziska J RosserDepartment of Pediatrics, School of Medicine, Division of Pulmonology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Tregony C SimoneauDepartment of Pediatrics, Harvard Medical School, Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-2407-4402
Jade Tam-WilliamsDepartment of Pediatrics, Pediatric Pulmonary Medicine, University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.
Kelan G TantisiraDivision of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, California, USA.
William AndersonDepartment of Pediatrics, University of Colorado School of Medicine, Allergy and Immunology Section, Children's Hospital Colorado, Aurora, Colorado, USA.
Jonathan M GaffinDepartment of Pediatrics, Harvard Medical School, Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-2213-4504
Theresa W GuilbertDepartment of Pediatrics, Division of Pediatric Pulmonology, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, USA.
Erick FornoDivision of Pulmonology Allergy/Immunology and Sleep Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0001-6497-9885

Funding

Multifactorial Asthma Determinants in Underresourced Pediatric PopulationsK23HL174407 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI Akilah Andrea Jefferson · 2024 to 2026
$494k
NHLBI NIH HHS K23 HL174407
6 · The paper itself

Abstract

backgroundSevere and difficult to treat asthma in children is a complex condition causing significant morbidity and associated healthcare costs. While treatment guidelines exist for severe asthma, optimal treatment approaches for the pediatric population are less well established. Furthermore, best practices regarding real world management and implementation of guidelines for the severe pediatric asthma population are lacking. In order to provide care for this population, institutions around the United States have developed multidisciplinary severe pediatric asthma programs (SPAPs). In recent years, the North American Severe Pediatric Asthma Consortium (NASPAC) was established as a mechanism for SPAPs to collaborate and share expertise in pediatric severe asthma. We describe the structure of the individual programs within NASPAC, as well as similarities and differences between them.

methodsStudy design consisted of a cross-sectional observational framework model, utilizing a Redcap survey that was distributed to sixteen SPAPs in 2024. Survey questions included total and new patient volume, type of staff, frequency of SPAP sessions, eligibility criteria for enrollment in the SPAP, and typical initial evaluation once enrolled. Twelve centers had completed prior surveys regarding patient volume in 2018 and 2021, and this data was used for comparison.

resultsFourteen centers responded to the 2024 survey. The centers were most similar in their incorporation of core personnel (pulmonologists, allergists, social workers, asthma educators), and the morbidity measures used for their clinic inclusion criteria. Almost all SPAPs had a basic initial evaluation including medication and technique review, adherence evaluation/discussion and spirometry. Significant variability was seen in presence of additional staff (psychologists, endocrinologists, nutritionists), and additional radiologic and laboratory testing at initial evaluation. DISCUSSION: Significant similarities exist among fourteen independent severe pediatric asthma programs throughout the United States. However, practice variability was evident between centers. The formation of NASPAC provides opportunities for research and collaborative initiatives, as well as to establish best practices for real world management of the severe and difficult to treat pediatric asthma population.

Indexed as

AsthmaPractice Patterns, Physicians'ChildCross-Sectional StudiesFemaleHumansPractice Guidelines as TopicSeverity of Illness IndexUnited States

Identifiers

PMID42464779
PMCPMC13377302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.