Evidence map›Paper›PMID 42464575›Full record

ReviewJournal of integrative plant biology2026

14-3-3 proteins: Central hubs in plant development and stress adaptation.

Jiale Yuan, Qizhang Wang, Jing Cao, Furong Wang, Hua Zhou, Jigang Li, Fang Lin

Abstract readReview
In one paragraph

Review in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiale YuanMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.ORCID https://orcid.org/0000-0002-9475-1192
Qizhang WangMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.ORCID https://orcid.org/0000-0003-0861-3410
Jing CaoMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.ORCID https://orcid.org/0000-0003-1353-7264
Furong WangMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.ORCID https://orcid.org/0009-0009-1722-862X
Hua ZhouLaboratory of Plant and Environment Interaction Study, Tsientang Institute for Advanced Study, Hangzhou, 310000, China.ORCID https://orcid.org/0000-0002-4944-058X
Jigang LiState Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-4395-2656
Fang LinMinistry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.ORCID https://orcid.org/0000-0002-6901-2048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

14-3-3 proteins are evolutionarily conserved regulators that orchestrate diverse physiological processes by binding to phosphorylated client proteins. These interactions modulate client activity, localization, stability, or interactome composition, thereby coordinating plant growth, development, metabolism, and stress responses. Mounting evidence underscores their direct involvement in phytohormone signaling and stress-response pathways, in which 14-3-3 binding often constitutes a key regulatory event. This review highlights recent advances elucidating the pivotal role of 14-3-3 proteins in regulating phytohormone networks, biotic and abiotic stress tolerance, and evolutionary adaptations. We position 14-3-3 proteins as crucial integrators of internal signals and external cues, serving as central hubs that rewire cellular networks to enable adaptation to complex, changing environments.

Indexed as

14-3-3 ProteinsAdaptation, PhysiologicalPlant DevelopmentStress, PhysiologicalPlant Growth RegulatorsPlant ProteinsSignal Transduction14-3-3 ProteinsPlant Growth RegulatorsPlant Proteins14‐3‐3 proteinsbiotic and abiotic stressevolutionaryphytohormone

Identifiers

PMID42464575
PMCPMC13446622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.