ArticleZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2026
[Changes in knee kinematic parameters and plasma inflammatory factors at different stages after anterior cruciate ligament injury].
Article in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the six-degree-of-freedom (6-DOF) kinematic characteristics of the knee joint and changes in plasma inflammatory factors during the acute and non-acute phases following anterior cruciate ligament (ACL) injury, thereby providing clinical evidence for the necessity of early intervention after ACL injury. Methods: Patients with ACL injury admitted between August 2024 and June 2025 were enrolled. A total of 56 patients met the inclusion criteria, including 24 in the acute phase (disease duration<30 days) and 32 in the non-acute phase (disease duration≥30 days). Thirty healthy volunteers served as the control group. No significant difference was observed among the three groups in baseline characteristics ( Results: Gait analysis showed that compared with the control group, the flexion/extension angle decreased and the anterior/posterior displacement increased in both the acute and non-acute phase groups; the varus/valgus angle and internal/external rotation angle also increased in the non-acute phase group; all differences were significant ( Conclusion: After ACL injury, characteristic dynamic knee instability and a pro-inflammatory microenvironment persist simultaneously. This dual mechanical and biological disturbance may constitute the pathological basis for the development and progression of post-traumatic osteoarthritis, underscoring the necessity of early intervention.
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