ArticleVirology journal2026
NGS-diagnosed HBV encephalitis with isolated left parietal lobe involvement: a case report.
Article in Virology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundViral encephalitis refers to the inflammation of the brain parenchyma caused by viral infection, usually manifested as fever, unconsciousness, seizures, and meningeal irritation symptoms. The non-specific clinical manifestations, combined with incomplete medical history, often lead to missed diagnoses and inappropriate treatments. CASE PRESENTATION: We present a case of Hepatitis B virus (HBV) encephalitis, manifesting as isolated left parietal lobe involvement. The patient is a chronic hepatitis B virus carrier who did not receive antiviral therapy. Upon onset, the main symptoms were unconsciousness, fever, and seizures. He was diagnosed with HBV encephalitis thru next-generation sequencing (NGS) testing of the cerebrospinal fluid (CSF). After antiviral treatment with entecavir and general symptomatic treatment, the patient's clinical symptoms disappeared, and a follow-up brain MRI showed that the lesion had almost completely resolved.
conclusionsCentral nervous system (CNS) infections caused by HBV are incredibly uncommon in clinical practice. This case highlights that the clinical manifestations of HBV encephalitis are nonspecific and prone to being missed, while neuroimaging often reveals an isolated lesion. Early application of NGS for accurate pathogen diagnosis is crucial to reduce misdiagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.