Evidence map›Paper›PMID 42464170›Full record

SynthesisBMC pediatrics2026

Adverse events in neonates with congenital heart disease after cardiovascular surgery: a systematic review and meta-analysis.

Emanuel Nunes, Renata Cristina de Campos Pereira Silveira, Fernanda Raphael Escobar Gimenes, Rosana Aparecida Pereira, Daiane Gabiattia

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emanuel NunesRibeirão Preto College of Nursing, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-902, Brazil.
Renata Cristina de Campos Pereira SilveiraRibeirão Preto College of Nursing, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-902, Brazil.
Fernanda Raphael Escobar GimenesRibeirão Preto College of Nursing, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-902, Brazil. fregimenes@eerp.usp.br.
Rosana Aparecida PereiraRibeirão Preto College of Nursing, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-902, Brazil.
Daiane GabiattiaRibeirão Preto College of Nursing, University of São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-902, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeonates with congenital heart disease (CHD) undergoing cardiovascular surgery are exposed to complex postoperative care and may experience adverse events.

methodsA systematic review and meta-analysis was conducted. Searches were performed in the Cochrane Central Register of Controlled Trials, LILACS, CINAHL, EMBASE, PubMed, Web of Science Core Collection, and Scopus. Observational cohort studies evaluating adverse events in neonates were eligible for inclusion. Data extraction was performed independently by two reviewers; in the event of disagreement, a third reviewer was consulted. Search results were exported to the online reference management software EndNote Basic for duplicate removal and subsequently imported into the Rayyan platform.

resultsOf the 60 articles identified, 20 studies comprising a total of 25,422 neonates with congenital heart disease in the postoperative period were included. The overall prevalence of adverse events was 14%. The most prevalent events were central venous catheter (CVC)-related incidents (14%), healthcare-associated infections (12%), and extubation failure (11%).

conclusionsThe prevalence of adverse events in neonates with CHD undergoing cardiovascular surgery is substantial and likely underreported. Further studies are needed to improve the detection, mitigation, and reduction of these events.

Indexed as

Cardiac Surgical ProceduresCardiovascular Surgical ProceduresHeart Defects, CongenitalPostoperative ComplicationsAirway ExtubationHumansInfant, NewbornAdverse eventsCardiovascular surgeryCongenital heart diseaseNeonatesPatient safety

Identifiers

PMID42464170
PMCPMC13662979

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.