Observational studyBMC oral health2026
Evaluation of the association between magnesium depletion score and wound healing following the extraction of lower impacted third molars: a prospective observational cohort study.
Observational study in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06891846 (Evaluation of the Relationship Between Magnesium Depletion Score And Socket Healing Following Tooth Extraction), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Evaluation of the Relationship Between Magnesium Depletion Score And Socket Healing Following Tooth Extraction
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the association between the Magnesium Depletion Score (MDS) and post-extraction soft tissue healing (STH) following lower impacted third molar (LITM) extraction in a medically healthy population.
methodsThis prospective observational cohort study was conducted at a single center. For standardization, only teeth that met predefined criteria were included. All participants were healthy, non-smoking adults undergoing single-tooth extraction. MDS was calculated pre-operatively. The Inflammatory Proliferative Remodelling (IPR) index was used to assess STH on days 4 and 14 and at week 6.
resultsA total of 111 participants (68 females, 43 males; mean age 36.5 ± 18.2 years) were included. Total IPR scores ranged from 6 to 16, while MDS ranged from 0 to 2 due to the absence of alcohol consumption. No significant associations were observed between MDS and sex (p = 0.265), or between MDS and IPR outcomes (both subscale and total scores; p = 0.348, p = 0.667, p = 0.569, and p = 0.179, respectively). In contrast, age was significantly associated with MDS (p = 0.02). IPR subscale and total scores were not significantly associated with sex (p = 0.679, p = 0.294, p = 0.296, and p = 0.179, respectively), age (p = 0.407, p = 0.770, p = 0.293, and p = 0.105, respectively), or serum magnesium levels (p = 0.221, p = 0.453, p = 0.880, p = 0.315, respectively).
conclusionsNo significant association was observed between MDS and STH, suggesting a limited predictive value in this population of healthy, alcohol-absent individuals.
trial registrationThe study was registered with ClinicalTrials.gov under the identifier NCT06891846 on 02-04-2025.
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