Evidence map›Paper›PMID 42463648›Full record

ArticleNature communications2026

High-gain and broadband in vivo amplifiers enabled by matched materials.

Yuting Zheng, Qi Li, Xinyue Wang, Chengwen Wu, Ju-Peng Chen, Zhibo Ren, Yiheng Chen, Xiran Pan, Xun Lei, Wenlong Li and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Yuting Zheng *Engineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Qi Li *Engineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Xinyue WangSchool of Biomedical Engineering, Tsinghua University, Beijing, China.
Chengwen WuEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Ju-Peng ChenEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Zhibo RenEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Yiheng ChenEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Xiran PanEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Xun LeiEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Wenlong LiEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Zhiyuan XiongEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Gao-Yang GeEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Wenxi SunEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Peiyun LiEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.ORCID http://orcid.org/0000-0001-7805-527X
Suqing GaoEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Biqin YangEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Siqi FangEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.
Jingcao XuEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-2497-8877
Jia-Tong LiEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China.ORCID http://orcid.org/0000-0003-1719-4713
Xiaochuan DaiSchool of Biomedical Engineering, Tsinghua University, Beijing, China. xcdai@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-1876-8558
Ting LeiEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China. tinglei@pku.edu.cn.ORCID http://orcid.org/0000-0001-8190-9483
Zhi ZhangEngineering Research Center of Ministry of Education for Adaptive Biomaterials and Medical Devices, School of Materials Science and Engineering, Peking University, Beijing, China. zhizhang@pku.edu.cn.ORCID http://orcid.org/0000-0002-1100-5523

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22172085National Natural Science Foundation of China (National Science Foundation of China) 52403219National Natural Science Foundation of China (National Science Foundation of China) T2425010Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 2262050
6 · The paper itself

Abstract

In-sensor biosignal amplification could enable superior signal quality, lower data transmission redundancy, and enhanced device integration. Organic electrochemical transistor (OECT)-based circuits offer an attractive candidate due to their low-voltage operation, high transduction efficiency, and seamless interfacing with biological tissues. However, the fundamental design principles governing high-performance OECT-based amplifiers, particularly the coupling between material design and circuit-level performance, remain insufficiently understood. Here, we present a matched n-p material system to elucidate the design principles and in-sensor amplification capability of complementary OECT circuits. Specifically, we develop a high-performance, low-operation-voltage n-type polymer, P(lgFTDPP-2FT), and integrate it with a complementary p-type DPP polymer. The resulting inverter-based amplifier can operate at low voltage while demonstrating a high gain exceeding 800 V V

Identifiers

PMID42463648
PMCPMC13639057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.