Evidence map›Paper›PMID 42463573›Full record

SynthesisAttention, perception & psychophysics2026

Arousal and attentional processes in the relationship between pain and time perception: Evidence from a systematic review and meta-analytic structural equation modeling.

Chunhua Xiao, Huazhan Yin, Dehua Wu

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Attention, perception & psychophysics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chunhua XiaoHunan Normal University, School of Education Science, No. 36 Lushan Road, Changsha, 410081, Hunan, China.
Huazhan YinHunan Normal University, School of Education Science, No. 36 Lushan Road, Changsha, 410081, Hunan, China. yhz1979@hunnu.edu.cn.
Dehua WuHunan Normal University, School of Education Science, No. 36 Lushan Road, Changsha, 410081, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distortions in time perception under pain have been widely reported, yet the mechanisms underlying these effects remain unclear. The Attentional Gate Model and prior empirical research indicate that attention and arousal are associated with pain and time perception, yet their roles remain unexamined in a unified framework. The study aimed to investigate the mediating roles of arousal, attention control, and attention bias in the relationship between pain and time perception. A systematic search of China National Knowledge Infrastructure, Wanfang, Web of Science, and PubMed identified studies reporting associations among pain, arousal, attention control, attention bias, and time perception. A two-stage meta-analytic structural equation modeling approach was used to test mediation, with multilevel meta-regression analyses examining moderation by age, gender, pain type, and target duration. A total of 154 articles (176 independent studies) were included. Pain was positively correlated with time perception, arousal, and attention bias. Both arousal and attention bias were positively correlated with time perception, while arousal was negatively correlated with attention control and attention bias. Mediation analysis showed that only arousal had a significant mediating effect. Moderation analysis indicated that age, gender, and target duration significantly moderated the relationships between attentional processes and time perception, with age additionally moderating the relationship between attention control and attention bias. Overall, arousal showed a mediating role between pain and time perception, while attentional effects are context-dependent. This study extends the Attentional Gate Model to pain and clarifies the roles of arousal and attentional mechanisms in temporal experience under pain. OPEN PRACTICES STATEMENT: This study was preregistered on the Open Science Framework ( https://osf.io/suzhn/ ). The data and code are publicly available online ( https://osf.io/3ucvb/ ).

Indexed as

ArousalAttentionAttentional BiasPainPain PerceptionTime PerceptionHumansLatent Class AnalysisArousalAttentionAttentional Gate ModelPainTime perception

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.