Evidence map›Paper›PMID 42463521›Full record

Observational studyScientific reports2026

Non-invasive estimation of inspiratory muscle pressure and work of breathing by airway pressure extrapolation from the P0.1 maneuver during assisted ventilation.

Friederike Behmüller, Tatiana Maria Bastian, Helene Selpien, Christine Eimer, Norbert Weiler, Dirk Schädler, Giacomo Bellani, Tobias Becher

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Friederike BehmüllerDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Tatiana Maria BastianDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Helene SelpienDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Christine EimerDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Norbert WeilerDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Dirk SchädlerDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Giacomo BellaniCentre for Medical Sciences - CISMed, University of Trento, Trento, Italy.
Tobias BecherDepartment of Anesthesiology and Operative Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. tobias.becher@uksh.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring inspiratory effort during assisted mechanical ventilation is essential to balance lung protection and respiratory muscle loading. Esophageal pressure monitoring remains the reference standard for estimating inspiratory muscle pressure and work of breathing but is invasive and rarely used in routine clinical practice. Non-invasive alternatives based on routinely available ventilator signals are therefore needed. This monocentric physiological substudy of the ICEBERG observational trial included adult patients with acute hypoxemic respiratory failure undergoing assisted mechanical ventilation. Inspiratory muscle pressure (P

Indexed as

Respiration, ArtificialRespiratory InsufficiencyRespiratory MusclesWork of BreathingAgedAirway ResistanceFemaleHumansInhalationMaleMiddle AgedPressureAcute hypoxemic respiratory failureAssisted ventilationEsophageal pressureInspiratory muscle pressureP0.1Work of breathing

Identifiers

PMID42463521
PMCPMC13377170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.