ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2026
Impact of inspiratory muscle training on inspiratory muscle metaboreflex in patients with heart failure with preserved ejection fraction.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
High inspiratory muscle work elicits respiratory muscle metaboreflex activation, contributing to increases in mean arterial pressure (MAP) and decreases in leg blood flow in adults at rest. Patients with heart failure with preserved ejection fraction (HFpEF) have exaggerated cardiovascular responses with inspiratory muscle metaboreflex activation. The purpose of this study was to investigate the effect of inspiratory muscle training (IMT) on respiratory muscle metaboreflex-mediated cardiovascular responses in patients with HFpEF. Thirteen patients with HFpEF (6 M/7 F; 69 ± 9 yr; 33 ± 5 kg·m
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