Evidence map›Paper›PMID 42462266›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026

Hyperoxic cerebral vasoconstriction in healthy humans: global, lobe, and regions of interest.

Hedyeh Khademi Motlagh, Travis L Haley, Kaylin D Didier, Jessica D Muer, Brett M Wannebo, Sophie Sanchez, Marlowe W Eldridge, Oliver Wieben, Kevin M Johnson, William G Schrage

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hedyeh Khademi MotlaghDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Travis L HaleyDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Kaylin D DidierDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0000-0002-0281-8493
Jessica D MuerDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Brett M WanneboDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0009-0003-4201-7791
Sophie SanchezDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0000-0001-9650-055X
Marlowe W EldridgeDepartment of Pediatrics, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0000-0003-3636-1679
Oliver WiebenDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0000-0002-7931-1930
Kevin M JohnsonDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.
William G SchrageDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin, United States.ORCID 0000-0002-4674-1344

Funding

Human cerebral blood flow regulation: sex, mechanism, and stress differencesR01HL150361 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SCHRAGE, WILLIAM G · 2020 to 2024
$3.0M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 5R01HL150361NHLBI NIH HHS R01 HL150361
6 · The paper itself

Abstract

Hyperoxia is used for hypoxia/ischemia-related conditions, but is associated with poorer clinical outcomes, potentially related to reductions in cerebral blood flow (CBF). Global CBF hyperoxia responses are variable; limited evidence suggests heightened sensitivity in anterior brain regions, leaving important gaps in understanding spatial resolution. Using 3-Tesla magnetic resonance imaging (MRI), we tested the hypotheses that

Indexed as

BrainCerebrovascular CirculationHyperoxiaVasoconstrictionAdultBlood PressureFemaleGray MatterHumansMagnetic Resonance ImagingMaleOxygenYoung AdultOxygenbrain blood flowbrain imagingcerebrovascular regulationmagnetic resonance imagingoxygen therapy

Identifiers

PMID42462266
PMCPMC13474392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.