Evidence map›Paper›PMID 42461552›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Surface Immobilization of Metalloenzymes Usinga Pyrene-Modified Hydrogel.

Nunzio Carducci, Chase Bruggeman, Sunanda Dey, Lincoln Mtemeri, David P Hickey

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nunzio CarducciDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, 48824, USA.
Chase BruggemanDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, 48824, USA.
Sunanda DeyDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, 48824, USA.
Lincoln MtemeriDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, 48824, USA.
David P HickeyDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, 48824, USA. hickeyd6@msu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrene-modified hydrogels are useful materials for preparing thin enzyme-containing polymer coatings on solid surfaces. Cross-linked films of pyrene-modified linear poly(ethylenimine) (pyrene-LPEI) contain a network of ionic bonds and π-π interactions. The hydrogels are uniformly thin (~1 μm) and porous, allowing fast diffusion of small molecule substrates, making these materials ideal for applications in catalysis. Pyrene-LPEI has been particularly useful to promote bioelectrocatalysis in several different metalloenzymes, including laccase (reduction of O

Indexed as

Enzymes, ImmobilizedHydrogelsLaccaseMetalloproteinsPyrenesBiosensing TechniquesElectrochemical TechniquesElectrodesNitrogenaseOxidation-ReductionPolyethyleneimineEnzymes, ImmobilizedHydrogelsLaccaseMetalloproteinsNitrogenasePolyethyleneiminepyrenePyrenesBioelectrocatalysisBiofuel cellBiosensorElectrochemical synthesisLaccaseLPEIPi stackingPyrene

Identifiers

PMID42461552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.