Evidence map›Paper›PMID 42461527›Full record

ArticleJournal of autism and developmental disorders2026

Investigating the Autism Diagnostic Observation Schedule 'Gold Standard' Origin Myth.

Larry Cashion, Philomena K Holdforth

Abstract read
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In one paragraph

Article in Journal of autism and developmental disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Larry CashionEnable Plus, 44 Ovens Street, Melbourne, VIC, 3013, Australia. support@enableplus.com.au.ORCID http://orcid.org/0009-0002-8505-8625
Philomena K HoldforthEnable Plus, 44 Ovens Street, Melbourne, VIC, 3013, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Autism Diagnostic Observation Schedule (ADOS) is regularly cited as the standalone 'gold standard' or an essential inclusion for diagnosis of Autism Spectrum Disorder. This research considers whether the evidence is consistent with the strength of such beliefs.

methodsA random sample of 100 published articles referring to the ADOS as having 'gold standard' status was reviewed. Analysis of cited evidence for this proposition was performed over three iterations, exploring the source of each 'gold standard' statement.

resultsThe first iteration found 62% of 'gold standard' statements were either unreferenced or only cited test materials. From the remaining 38%, a total of 47 discrete sources were referenced. In the second iteration, about 60% of papers did not include any supporting reference, with another five citing references inconsistent with 'gold standard' statements. Only one paper from the third iteration cited source material that had not been reviewed in the first and second iterations. Two of the three associated references cited in that one paper contained no mention of the ADOS as a 'gold standard'.

conclusionThe majority of papers reviewed failed to cite support for a 'gold standard' statement. Failure to identify these issues at peer-review suggests a pervasive, but erroneous, assumption that there is a broad consensus about the status of the ADOS. In reviewing this sample, 'gold standard' consensus appears based more on hearsay and marketing than clinical support, suggesting a need for greater vigilance during the review process by requiring authors to establish evidence for significant assertions.

Indexed as

ADOSAutismAutism diagnostic observation scheduleAutism spectrum disorderDiagnosisGold standard

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.