ArticleHead and neck pathology2026
Parotid Cystadenoma Presenting as Recurrent Parotitis: A Five-Case Retrospective Series and Preliminary Clinicopathological Features.
Article in Head and neck pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeParotid cystadenoma is an uncommon benign epithelial salivary gland neoplasm. Rarely, it may present with recurrent inflammatory episodes, creating diagnostic uncertainty and operative complexity. To the authors' knowledge, this represents the largest reported case series specifically focused on histologically confirmed parotid cystadenoma presenting with recurrent parotitis. This case series describes five such patients and outlines preliminary clinicopathological features that may support recognition of this presentation, while acknowledging the exploratory nature of the observations.
methodsWe performed a retrospective descriptive case series from a specialist parotid surgical practice. Five consecutive patients managed by the primary author with histologically confirmed parotid cystadenoma and a clinical history of recurrent parotitis were included. Clinical presentation, imaging, tissue sampling, operative findings, histopathology, facial nerve status and 12-month follow-up were reviewed from clinical records. No formal diagnostic criteria were developed or validated.
resultsAll patients had unilateral cystic parotid lesions with recurrent inflammatory symptoms. Imaging demonstrated benign-appearing cystic lesions, varying from well-circumscribed superficial-lobe cysts to multiloculated lesions extending into the deep lobe. Preoperative core biopsy was non-diagnostic in all cases, usually yielding cyst fluid, inflammatory debris or degenerate cells. Surgical excision established the diagnosis in each patient. Histology confirmed cystadenoma, predominantly oncocytic; intraluminal crystalloids were identified in two cases, both associated with suppurative or inflammatory change. No patient had preoperative facial nerve dysfunction. At 12-month follow-up, no recurrence or persistent postoperative facial nerve deficit was recorded in any case.
conclusionParotid cystadenoma should be included in the differential diagnosis of recurrent parotitis associated with a cystic parotid lesion, particularly when tissue sampling is inconclusive. The proposed clinicopathological features are preliminary observations from a small retrospective series and require validation in larger cohorts before use as diagnostic criteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.