Trial reportEuropean journal of applied physiology2026
Intensity matters: high-intensity interval resistance exercise induces greater immune activation than low-intensity resistance exercise 45 min post-workout.
Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Circulating Myokine Responses to Acute Endurance Exercise and Their Role in Immunoregulation: A Systematic Review and Meta-Analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAcute physical exercise triggers a transient immune response. For endurance exercise, these effects are intensity-dependent. In contrast, the role of exercise intensity in resistance exercise (RE) and its contribution to immune modulation remains less understood. This randomised crossover trial aims to compare the acute effects of High-Intensity Interval Resistance Exercise (HIIRE) versus Low-Intensity Resistance Exercise (LIRE) on routine clinical cellular inflammatory markers-neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII)-in 24 healthy, RE-trained young men.
methodsMeasurements were taken at baseline (T
resultsBaseline-adjusted ANCOVAs revealed significant interactions for cellular inflammatory markers (η
conclusionThe results suggest a complex immune response involving pro-inflammatory signalling and immune cell redistribution induced by acute RE, with intensity being a main driver. This underscores the pivotal role of intensity in modulating acute immune responses to RE, with potential implications for exercise prescription targeting inflammatory processes.
Indexed as
Identifiers
42461394What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.