Evidence map›Paper›PMID 42461335›Full record

ArticleJournal of gastrointestinal cancer2026

Preoperative CT Assessment of Portal Vein Contact Length Predicts Poor Prognosis in Resectable Pancreatic Head Cancer.

Shingo Kozono, Takaaki Tatsuguchi, Atsushi Fujii, Hirotaka Kuga, Keisuke Hirahata, Yuzo Shimokawa, Masayuki Hijioka, Masato Sakamoto, Sadafumi Tamiya, Toru Nakano

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Article in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shingo KozonoDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan. shingo_kozono01@kitakyu-cho.jp.ORCID http://orcid.org/0000-0003-3898-6373
Takaaki TatsuguchiDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.ORCID http://orcid.org/0000-0002-4156-4991
Atsushi FujiiDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.ORCID http://orcid.org/0000-0002-9106-9227
Hirotaka KugaDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.
Keisuke HirahataDepartment of Gastroenterology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.
Yuzo ShimokawaDepartment of Gastroenterology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.ORCID http://orcid.org/0000-0001-9529-2293
Masayuki HijiokaDepartment of Gastroenterology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.
Masato SakamotoDepartment of Cardiovascular Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.
Sadafumi TamiyaDepartment of Pathology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.
Toru NakanoDepartment of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-Ku, Kitakyushu, Fukuoka, 802-8561, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether preoperative computed tomography (CT)-based tumor-portal/superior mesenteric vein (PV/SMV) contact angle and contact length predict pathological venous invasion and refine prognostic stratification in anatomically resectable pancreatic ductal adenocarcinoma (R-PDAC).

methodsWe retrospectively reviewed 108 patients who underwent upfront pancreaticoduodenectomy without neoadjuvant chemotherapy for pancreatic head PDAC, including 101 anatomically resectable cases and 7 borderline resectable cases with PV involvement (BR-PV). Tumor-PV/SMV contact angle and contact length were measured on multidetector CT. Their associations with pathological PV/SMV invasion, PV/SMV resection, and overall survival (OS) were analyzed.

resultsBoth contact angle and contact length predicted pathological venous invasion, with optimal cutoff values of 90° for angle (AUC = 0.86) and 15 mm for length (AUC = 0.84), and both were significantly associated with pathological venous invasion and PV/SMV resection (all p < 0.001). In the subgroup with R-PDAC, however, only contact length provided meaningful prognostic stratification. Patients with contact length ≥ 15 mm had significantly worse OS than those with contact length < 15 mm (p = 0.0032) or no contact (p < 0.001), and their survival was comparable to that of BR-PV patients (p = 0.8548). In multivariable analysis, contact length ≥ 15 mm remained an independent adverse prognostic factor (HR 2.79, 95% CI 1.64-4.73, p < 0.001).

conclusionPreoperative CT-based assessment of tumor-PV/SMV contact length may serve as a practical marker for identifying a high-risk subgroup within R-PDAC and may help refine selection of patients for neoadjuvant treatment.

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsPortal VeinAgedFemaleHumansMaleMesenteric VeinsMiddle AgedMultidetector Computed TomographyNeoplasm InvasivenessPancreaticoduodenectomyPreoperative CarePrognosisRetrospective StudiesTomography, X-Ray ComputedComputed tomographyPancreatic ductal adenocarcinomaPortal vein invasionResectable pancreatic head cancerSuperior mesenteric vein involvementTumor–vessel contact

Identifiers

PMID42461335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.