Evidence map›Paper›PMID 42461277›Full record

ArticleInternational urogynecology journal2026

Should Maximum Urethral Closure Pressure Be Measured on Prolapse Reduction?

Hans Peter Dietz, Ka Lai Shek, Joseph Descallar

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Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Hans Peter DietzSydney Urodynamic Centres, Sydney, Australia. hpdietz2@bigpond.com.ORCID http://orcid.org/0000-0002-2211-6149
Ka Lai ShekLiverpool Clinical School, Western Sydney University, Sydney, Australia.
Joseph DescallarIngham Institute for Applied Medical Research, Liverpool, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisMaximum urethral closure pressure (MUCP) is a measure of urethral quality and is associated with urodynamic stress incontinence (USI). A confounder of this relationship is pelvic organ prolapse (POP). We investigated the effect of prolapse reduction on MUCP and its association with USI.

methodsWe carried out an observational study using data sets of 1992 women seen at a tertiary urogynaecological centre in 2017-2024. All had undergone a questionnaire, POPQ examination and translabial ultrasound. MUCP was obtained after bladder emptying, at rest and during POP reduction. USI was rated mild, moderate, marked or severe. Associations between MUCP/MUCP on prolapse reduction and USI were tested using nominal regression. Nagelkerke R

resultsOf 1992 women seen for urodynamic testing, 1737 had MUCP obtained at rest and POP reduction. Most complained of stress urinary incontinence (72.8%), and 7% reported splinting to void. On clinical examination, 82.8% had significant prolapse. USI was diagnosed in 61.9%, detrusor overactivity in 22.6% and voiding dysfunction in 31.9%. Mean MUCP was 39.1 cm H

conclusionsSymptoms of splinting and objective prolapse on POPQ predict a lower MUCP on prolapse reduction. However, as the latter does not significantly increase predictive value, prolapse reduction is probably unnecessary in clinical practice.

Indexed as

3D/4D ultrasoundMaximum urethral closure pressurePelvic organ prolapseStress urinary incontinenceUrethral closureUrethral kinking

Identifiers

PMID42461277

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.