Evidence map›Paper›PMID 42461239›Full record

Trial reportJournal of hospital medicine2026

Pediatric home-based central venous access device dressings: Medical liquid adhesive versus standard care to reduce dressing disruption: The STICKY-kids RCT protocol.

Tricia M Kleidon, Mari Takashima, Victoria Gibson, Robert S Ware, R N Nicole Marsh, Amanda J Ullman

Abstract readRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Journal of hospital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tricia M KleidonQueensland Children's Hospital, Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-8369-3970
Mari TakashimaQueensland Children's Hospital, Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-1167-9106
Victoria Gibson
Robert S WareGriffith Biostatistical Unit, Griffith University, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-6129-6736
R N Nicole MarshSchool of Nursing and Midwifery, Alliance for Vascular Access Teaching and Research (AVATAR), Griffith University, Nathan, Queensland, Australia.ORCID https://orcid.org/0000-0002-5779-1304
Amanda J UllmanQueensland Children's Hospital, Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-8860-5319

Funding

Eloquest Healthcare
6 · The paper itself

Abstract

backgroundCentral venous access devices (CVADs) are frequently used in Hospital-At-Home models to facilitate prolonged intravenous treatment for children. Premature CVAD dressing disruption is common and contributes to device failure. This protocol describes a trial evaluating the adjunctive use of medical liquid adhesive at the dressing-skin interface to improve dressing adhesion and maintain dressing integrity.

methodsThis single-site, two-arm, parallel-group, superiority randomized controlled trial undertaken in a children's Hospital-at-Home will evaluate whether adding medical liquid adhesive to standard CVAD dressings, compared with standard dressing alone, reduces dressing disruption. Children aged ≤18 years requiring a CVAD for ≥7 days will be randomized 1:1 to standard dressing plus medical liquid adhesive or standard dressing alone. Dressing integrity will be assessed daily, with dressing-related outcomes assessed after 7 days or following dressing change (whichever occurs first). At each dressing change, participants are eligible for repeat participation, retaining their original randomization. The primary outcome is dressing disruption requiring premature replacement or reinforcement before the scheduled 7-day change. Secondary dressing-related outcomes include dressing dwell-time, skin adverse events, CVAD complications, patient, caregiver, and clinician satisfaction. Secondary outcomes assessed once per participant are healthcare utilization and costs. Analyses will follow the intention-to-treat principle. DISCUSSION: Ensuring the safety and durability of invasive devices beyond the in-hospital setting is an increasing priority in pediatric care. This trial will provide rigorous data to inform the clinical- and cost-effectiveness of the addition of medical liquid adhesive to standard dressings to improve CVAD dressing integrity, supporting care across the hospital-to-home continuum.

Indexed as

AdhesivesBandagesCatheterization, Central VenousCentral Venous CathetersHome Care ServicesAdolescentChildChild, PreschoolFemaleHumansInfantMaleAdhesives

Identifiers

PMID42461239
PMCPMC13534884

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.