Evidence map›Paper›PMID 42461181›Full record

ArticleJACC. Case reports2026

High-Output Heart Failure and Pulmonary Hypertension Caused by Arteriovenous Graft: Diagnosis and Treatment.

Anju Bhardwaj, Subramanyan Valadi Ramakrishnan, Denny Joseph, Sriram Nathan, Igor D Gregoric, Maria Patarroyo

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anju BhardwajDepartment of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Subramanyan Valadi RamakrishnanDepartment of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Denny JosephDepartment of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Sriram NathanDepartment of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Igor D GregoricDepartment of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Maria PatarroyoDepartment of Advanced Cardiopulmonary Therapies and Transplantation, The University of Texas Health Science Center at Houston, Houston, Texas, USA. Electronic address: Maria.M.PatarroyoAponte@uth.tmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical arteriovenous (AV) fistulas provide vascular access for hemodialysis in patients with end-stage renal disease, but this low-resistance pathway can lead to high-flow circulation and cardiac decompensation. CASE SUMMARY: A 42-year-old woman with end-stage renal disease from chronic glomerulonephritis and a failed renal transplant resumed hemodialysis via a 22-year-old left-arm brachiocephalic AV graft. She developed high-output heart failure. We ligated the AV graft and placed a peritoneal dialysis catheter. Hemodynamic parameters were normal 6 months postligation. DISCUSSION: Treatment of high-output heart failure and pulmonary hypertension via permanent surgical ligation of an AV fistula is complicated. Ligation can improve cardiac function, but studies are not adequately powered to change practice. The risks and benefits of AV fistula ligation or removal must be reviewed carefully. TAKE-HOME MESSAGE: This case highlights that high-output heart failure is a serious complication of AV access in patients on dialysis, requiring careful diagnosis and multidisciplinary management.

Indexed as

circulationhemodynamicspulmonary hypertension

Identifiers

PMID42461181
PMCPMC13554870

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.