ArticleJACC. Case reports2026
Rapidly Progressive Immune-Mediated Meningococcal Pericarditis Presenting as Cardiac Tamponade.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Clinical Mirage: The Peril of Improving Laboratory Markers in Meningococcal-Induced Cardiac Tamponade.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPericardial involvement in meningococcemia is uncommon and often immune complex mediated. Initial effusions may appear insignificant but can rapidly progress to cardiac tamponade, even as systemic infection markers improve. CASE SUMMARY: A 65-year-old man presented with septic shock secondary to Neisseria meningitidis bacteremia. Initial imaging demonstrated a small pericardial effusion without clinical manifestations. Despite antibiotics and improving systemic markers, he developed sudden hemodynamic deterioration because of rapid effusion progression. Repeat echocardiography revealed tamponade physiology, necessitating emergent subxiphoid tube pericardiostomy. He was successfully stabilized through prompt intervention despite vasopressor dependence. DISCUSSION: This case illustrates a paradoxical clinical trajectory in immune complex-mediated meningococcal pericarditis, in which tamponade develops after bacteremic control. This dissociation between infectious and pericardial trajectories underscores the importance of serial imaging and proactive surgical planning independent of laboratory trends. TAKE-HOME MESSAGES: In meningococcal infection, hemodynamic instability despite improving infection markers should prompt urgent echocardiographic reassessment. Early recognition and timely drainage may be lifesaving.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.