Evidence map›Paper›PMID 42461174›Full record

ArticleJACC. Case reports2026

Subacute Stent Thrombosis Associated With Prasugrel Refractoriness in a Patient With Chronic ITP.

Masahiro Takeo, Hiroki Okabe, Keisuke Hidaka, Yutaro Naka, Koshi Setoyama, Masaharu Kataoka

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masahiro TakeoThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.
Hiroki OkabeThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan. Electronic address: hiro-okabe@med.uoeh-u.ac.jp.
Keisuke HidakaThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.
Yutaro NakaThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.
Koshi SetoyamaThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.
Masaharu KataokaThe Second Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo our knowledge, there have been no reports of stent thrombosis due to prasugrel nonresponse in patients with immune thrombocytopenia (ITP). CASE SUMMARY: A 66-year-old man with chronic ITP presented with an inferior ST-segment elevation myocardial infarction. The patient underwent drug-eluting stent implantation. On the sixth day, he developed recurrent chest pain. Coronary angiography revealed subacute stent thrombosis. P2Y DISCUSSION: This case demonstrates that stent thrombosis can occur in patients unresponsive to prasugrel and that PRU measurement may be useful even in ITP patients. TAKE-HOME MESSAGES: In ITP patients, it is necessary to carefully balance the risk of thrombosis with the risk of bleeding. Prasugrel nonresponse may contribute to stent thrombosis, and PRU may be useful for identifying prasugrel nonresponse in patients with ITP.

Indexed as

acute coronary syndromeantiplateletchest painstentsthrombosis

Identifiers

PMID42461174
PMCPMC13531062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.