Evidence map›Paper›PMID 42461049›Full record

ArticlemBio2026

OprF functions as a latch to direct outer membrane vesicle release in

Shrestha Mathur, Citrupa Gopal, Susan K Erickson, Leah R Goldberg, Sonia Hills, Abigail G B Radin, Jeffrey W Schertzer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shrestha Mathur *Department of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Citrupa Gopal *Department of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Susan K EricksonDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Leah R GoldbergDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Sonia HillsDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Abigail G B RadinDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.
Jeffrey W SchertzerDepartment of Biological Sciences, Binghamton University, Binghamton, New York, USA.ORCID 0000-0002-7658-0860

Funding

Small-molecule membrane interactions as a driver of bacterial outer membrane vesicle biogenesis across speciesR15GM135862 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI SCHERTZER, JEFFREY · 2020 to 2020
$448k
NIGMS NIH HHS 1R15GM135862NIGMS NIH HHS R15 GM135862
6 · The paper itself

Abstract

Bacterial outer membrane vesicles (OMVs) contribute to virulence, competition, immune avoidance, and communication. This has led to great interest in how they are formed. To date, investigation has focused almost exclusively on what controls the initiation of OMV biogenesis. Regardless of the mechanism of initiation, all species face a similar challenge before an OMV can be released: how does the outer membrane (OM) detach from the underlying peptidoglycan (PG) in regions that will ultimately bulge and then vesiculate? The OmpA family of OM proteins (OprF in

Indexed as

Bacterial Outer MembraneBacterial Outer Membrane ProteinsBacterial ProteinsPorinsPseudomonas aeruginosaCell WallPeptidoglycanBacterial Outer Membrane ProteinsBacterial ProteinsOprF protein, Pseudomonas aeruginosaPeptidoglycanPorinsOmpA familyOprFouter membrane proteinsouter membrane vesiclesporinprotein conformationPseudomonas aeruginosa

Identifiers

PMID42461049
PMCPMC13463901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.