Evidence map›Paper›PMID 42461018›Full record

ArticleMicrobiology spectrum2026

Acid exposure induces adaptive resistance in

Jordan L Chirumbolo, Amanda Hutsell, Amar Kosovac, Isabella Ihemis, Melissa J Whitford, Juliane Nguy, Rowan J Wolf, Damir Sarajlic, Topher Hunter, Matthew F Myntti and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jordan L ChirumboloDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Amanda HutsellNextScience LLC, Jacksonville, Florida, USA.
Amar KosovacDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Isabella IhemisDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Melissa J WhitfordDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Juliane NguyDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Rowan J WolfDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.
Damir SarajlicNextScience LLC, Jacksonville, Florida, USA.
Topher HunterNextScience LLC, Jacksonville, Florida, USA.
Matthew F MynttiNextScience LLC, Jacksonville, Florida, USA.
Terri N EllisDepartment of Biological Sciences, University of North Florida, Jacksonville, Florida, USA.ORCID 0000-0003-2519-7391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical irrigation solutions remove bacteria and disrupt biofilms to prevent nosocomial infections. This study evaluated the impact of combined treatment of a biofilm-disrupting lavage solution and antibiotic therapy. Bacteria treated with antibiotics and/or lavage were evaluated via broth microdilution and checkerboard assays.

Indexed as

AcidsAnti-Bacterial AgentsBiofilmsDrug Resistance, BacterialKlebsiella pneumoniaeBacterial Outer Membrane ProteinsEscherichia coliHumansHydrogen-Ion ConcentrationKlebsiella InfectionsMicrobial Sensitivity TestsPorinsStaphylococcus aureusAcidsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsPorinsantibiotic resistanceantibiotic toleranceKlebsiellaporins

Identifiers

PMID42461018
PMCPMC13435878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.