Evidence map›Paper›PMID 42460944›Full record

ArticleJACC. Case reports2026

Recurrent Pericarditis in a Rugby Player: Imaging-Guided Therapy.

Abdallah Abuawad, Osamah Badwan, Muhammad Ehsan, Chadi Thabaja, Faysal Massad, Muhannad Mahmoud, Besir Besir, Abdelrahman Ahmed, Jibran Ikram, Tom Kai Ming Wang and 1 more

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abdallah AbuawadCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Osamah BadwanCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Muhammad EhsanCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Chadi ThabajaCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Faysal MassadCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Muhannad MahmoudCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Besir BesirCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Abdelrahman AhmedCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Jibran IkramCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Tom Kai Ming WangCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Allan KleinCenter for the Diagnosis and Treatment of Pericardial Disease, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address: kleina@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent pericarditis in young athletes is challenging, as relapse risk, treatment duration, and return to play must be balanced. CASE SUMMARY: A 26-year-old rugby player developed recurrent pericarditis after atrial septal defect repair. At initial presentation, she had moderate pericardial late gadolinium enhancement on cardiac magnetic resonance (CMR) and a high pericarditis risk score, and she achieved clinical remission on rilonacept. At taper initiation, she was asymptomatic with normal inflammatory biomarkers yet showed mild residual late gadolinium enhancement on CMR. After tapering of rilonacept, she relapsed 11 months later but responded rapidly to reinitiation of therapy. DISCUSSION: This case highlights the challenges of recurrent pericarditis in a high-risk athlete and discusses athlete-specific considerations, including exercise restriction and individualized return to activity. It also suggests that serial CMR and clinical risk scores may provide supportive context for cautious tapering, although evidence remains limited. TAKE-HOME MESSAGES: This case demonstrates the complexity of recurrent pericarditis management in a high-risk athlete despite clinical and CMR improvement. Serial CMR and clinical risk scores may provide supportive, hypothesis-generating context for individualized care and cautious tapering.

Indexed as

athletescardiac MRIinterleukin-1 blockadelate gadolinium enhancementrecurrent pericarditisrilonacept

Identifiers

PMID42460944
PMCPMC13379883

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.