ArticleBiomedical optics express2026
Quantification and mitigation of system background fluorescence in fiber-optic-based imaging systems.
Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autofluorescence imaging provides a snapshot of tissue biochemistry that can be used to identify dysplastic tissue. However, deployment in multimodal single-fiber imaging systems is limited by system background fluorescence. We propose to improve the signal-to-background ratio (SBR) through the removal of background emission in fiber-optic catheters for autofluorescence and optical coherence tomography. We collected power and spectral measurements of optical components to characterize their emissions using 450 nm excitation. We measured the per-meter fluorescence contribution of single-mode, double-clad, and multimode optical fibers. By tailoring the detection filter to the emission spectra of the target tissue and system background, we have demonstrated an average of 7.9x improvement in SBR.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.