Evidence map›Paper›PMID 42460310›Full record

ArticleFrontiers in endocrinology2026

Development and validation of a prediction model for psychological distress in patients with differentiated thyroid cancer undergoing ¹³¹I therapy.

Lingling Zeng, Yiming Ma, Suyun Yang

Abstract readValidation Study
In one paragraph

Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Lingling ZengDepartment of Critical Care Medicine, Chongqing University Three Gorges Hospital, Wanzhou, Chongqing, China.
Yiming MaCollege of Nursing, Shanxi Medical University, Taiyuan, Shanxi, China.
Suyun YangDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To develop and validate a risk prediction model for psychological distress in patients with differentiated thyroid cancer (DTC) undergoing ¹³¹I therapy. Methods: A total of 247 DTC patients who received ¹³¹I therapy at a tertiary Grade A hospital in Taiyuan between May and December 2025 were enrolled. Independent risk factors for psychological distress were identified to construct the model. Model performance was evaluated using receiver operating characteristic (ROC) curves, the Hosmer-Lemeshow test, and calibration curves. Results: Multivariate logistic regression identified poor sleep quality, thyroid-stimulating hormone (TSH) stimulation, pulmonary metastasis, social support, radiation exposure concerns, and lower serum 25-hydroxyvitamin D levels as independent risk factors (all Conclusion: This internally validated model is a promising tool for predicting psychological distress in DTC patients undergoing ¹³¹I therapy. However, external validation in larger, multicenter cohorts is necessary before routine clinical use can be recommended.

Indexed as

Iodine RadioisotopesPsychological DistressStress, PsychologicalThyroid NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedNomogramsRisk FactorsROC CurveIodine-131Iodine Radioisotopes131I therapydifferentiated thyroid cancerprediction modelpsychological distressrisk factors

Identifiers

PMID42460310
PMCPMC13368564

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.